Revista Gen-T, Nº1 Internacional

Cholinesterase inhibitors in dementia

CONTENTS
ABSTRACT
INTRODUCTION
ALZHEIMER’S DISEASE PATHOGENESIS AND POTENTIAL PHARMACOLOGICAL TREATMENTS
THE CHOLINERGIC HYPOTHESIS AND DONEPEZIL
PHARMACOLOGICAL PROPERTIES
DONEPEZIL IN ALZHEIMER’S DISEASE
DONEPEZIL IN CEREBROVASCULAR DISORDERS
DONEPEZIL IN OTHER CNS DISORDERS
SIDE-EFFECTS AND MAJOR ADVERSE DRUG REACTIONS (ADRs)
DISCONTINUATION AND SWITCHING POLICIES
PHARMACOGENETICS AND PHARMACOGENOMICS
OPTIMIZATION OF ALZHEIMER’S DISEASE
THERAPEUTICS
CONCLUSIONS
REFERENCES