Medical Bulletin EuroEspes Health

Nº35, April 2023

Editorial Abril

  • The Word


Nervous System

  • Mechanism of STMN2 polyadenylation and its correction in TDP-43 proteinopathies (Amyotrophic Lateral Sclerosis and Fronto-Temporal Dementia).

    Biomarkers of Anxiety

  • Plastic and stimulus-specific coding of salient event stimuli in the central amygdala.

  • Habit-linked brain circuits light up in people with eating disorders (Anorexia, Bulimia).

  • The arduous search for treatments for Alzheimer's disease

  • Neuroimaging biomarkers of Alzheimer's disease

  • Neuroinflammation is associated with brain dysfunction in Alzheimer's disease.

  • Iron chelation therapy leads to worsening of Parkinson's disease

  • Ultrasonic ablation treatment for Parkinson's disease

  • Risk of epilepsy after suffering a reversible encephalopathy.

  • Communication between T-cells and the gut microbiome influences Multiple Sclerosis

  • Psychosis predictive instruments

  • A metabotropic glycine receptor

  • Anti-Tau neuronal immunotherapy

  • Mitochondrial metabolism establishes the specific rate of neuronal development in each species.

  • Dialogue between Astrocytes and Microglia

  • The brain connectome of the fly synapse by synapse

Cardiovascular and Cerebrovascular Disease

  • Autoimmune features of atherosclerosis

  • The link between obesity and autoimmunity

  • Endovascular treatment in stroke

  • Prevention of aortic dissection

  • Immediate versus staged complete revascularization in patients presenting with acute coronary syndrome and multivessel coronary artery disease.


  • Colorectal Cancer in Young People

  • Overcoming a barrier in prostate cancer

  • Control of the progression of glioblastoma multiforme.

  • Possible reduction of brain metastases caused by peripheral tumors

  • How air pollution causes lung cancer without harming DNA

  • STING inhibits reactivation of latent metastases in lung adenocarcinoma

  • Mutations in MEN1 mediate clinical resistance to menin inhibition in leukemia.


  • ASO for Angelman syndrome

  • Dominance and Recessivity

  • The mysteries of the inactive X chromosome

  • Public opinion on polygenic screening of embryos

  • Genome-based scores predict thousands of molecular traits in humans

  • Spatial multiomic map of trophoblast development in early pregnancy.

  • Generation of functional oocytes from male mice in vitro

  • Whole genome duplication drives oncogenic loss of chromatin segregation

  • Risk locus identified for pediatric astrocytoma

  • An atlas of genetic scores to predict multiomics traits


  • Epigenetics as a mediator of plasticity in cancer

  • Spatial epigenome-transcriptome profiling in mammalian tissues

  • MicroRNAs for blood development

  • Fitusiran, a gene silencer, for hemophilia treatment

  • A reader for H3K79me2

  • Suppression of Adenine methylation

  • The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutated leukemia.

Precision Medicine

  • Precision Medicine in Epilepsy

  • Precision Medicine for Psychosis


  • Precision Medicine in Psychiatry: Psychosis as a Paradigm

  • Health Impact of Migraine: Second leading cause of disability worldwide.

  • Genome-Environment Interaction in Autism

COVID-19 News

  • People who were contaminated with the Omicron variant are less likely to suffer from persistent COVID

  • Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children.

  • Report on COVID's origins sparks intense debate on GISAID genome center

  • Unnecessary alarms due to absurd political and sanitary decisions

  • SARS-CoV-2 surveillance in Huanan seafood market

COVID-19 News

  • A large viral arsenal and an excellent immune evasion system.
  • Trial settles debate on best design for mRNA in COVID vaccines
  • The latest COVID pandemic spike in China may be subsiding
  • Contact with Coronaviruses distorts immune capacity: The future of anti-COVID vaccines
  • Multiple Pathways for SARS-CoV-2 Resistance to Nirmatrelvir
  • New variants in China
  • Discrimination against people who did not get vaccinated during the pandemic
  • Antibiotics may regulate immune memory in vaccine recipients
  • with anti-SARS-CoV-2-mRNA vaccines
  • 65 million people suffer from persistent COVID worldwide
  • What will happen from now on with vaccines and anti-COVID behavior?
  • EuroEspes Health Medical Bulletin 4
  • Adjuvant-free intranasal herringbone vaccine elicits protective mucosal immunity to sarbecoviruses
  • Anti-COVID Vaccines Affect Menstruation
  • COVID-19 and brain aging
  • Molnupiravir against COVID could lead to viral mutations
  • Learning from the disastrous response to COVID

Original Articles

  • A single integral and sine qua non cause of all cancers. Salvador Harguindey, Julian Polo Orozco, Stephan J. Reshkin and Khalid Alfarouk



  • Mutation that causes night blindness in humans helps whale sharks see in the dark

  • Beethoven's diseases

  • Hairy and bald tomatoes

  • Fundamentals of empathy

  • Social learning in eusocial insects

  • Loss of lysosomes by lysophagia

  • The machinery that regulates apoptotic cell death

  • SUMO deactivates immunosurveillance

  • Physical exercise is not always helpful for fat reduction

  • Dwarf and giant species are more at risk of extinction

  • Learning to dance

  • Dual domestication and genetic variants of the grapevine

  • An intestinal bacterial strain rescues stunted growth. Lactiplantibacillus plantarum promotes growth in malnourished mice

  • Coding of sexual desire in the brain

  • Anxiety and irrelevant information

  • The underlying mechanism of psychedelic action

  • Labeling early trauma

  • Volatile sex pheromones of tsetse flies

  • Mutually interdependent relationship of the extracellular matrix and the immune system

  • Inhibition of cellular RNA methyltransferase abrogates influenza virus replication

  • Decrease in the benefits of urban life for the growth and development of children and adolescents.

  • Ancient DNA from centuries-old East African cities illuminates origins of Swahili culture

  • Intestinal enterochromaffin cells drive visceral pain and anxiety

  • The Spanish origin of American horses

Healthcare Market

  • Doubts about Alzheimer's drug research
  • Approval of lecanemab for the treatment of Alzheimer's disease generates controversy and backlash
  • New mRNA vaccine against respiratory syncytial virus
  • The therapeutic potential of psychedelics. The development of psychedelics as drugs faces several challenges
  • EuroEspes Health Medical Bulletin 5
  • Tuberculosis treatment failure associated with evolving antibiotic resilience.
  • Nucleoside-modified multivalent mRNA vaccine against all known influenza virus subtypes
  • ALS patient set record for communication through brain implant: Brain interfaces could allow paralyzed people to speak at near-normal speeds
  • Smart computing connects everything
  • Development of pig-to-human organ transplants

Health markets

  • Glucocorticoids calm cytokine storm

  • Multifunctional therapeutic peptides for corneal damage

  • New approaches in antitumor immunotherapy

  • Machine learning-assisted design for drug formulations

  • Super jumper robots without legs

  • Cholesterol Antibody Patent Dispute

  • Necessary changes in the conception and treatment of chronic pain.

  • Sparsentan in patients with IgA nephropathy.

  • Fezolinetant for the treatment of vasomotor symptoms in menopause

  • Garadacimab, a factor XIIa inhibitor, for the prevention of hereditary angioedema

  • Etrasimod as induction and maintenance therapy for ulcerative colitis

Disruptive topics

  • Commercial Determinants of Health


  • Dr. Miguel Pérez de Juan
  • Editorial May: Conditional Normality
  • Prevalent Diseases Prevention Campaign
  • New Genomic Biomarker for Alzheimer's disease
  • Nutraceutical Biotechnology
  • COVID-19 News
  • Promotional Section
Subscribe to the EuroEspes Health Medical Newsletter
Subscribe to the EuroEspes Health Medical Newsletter
Medical bulletin June Euroespes


Nº1, June 2020

  • Coronavirus control and protection plan
  • Effect of DefenVid as an immunopotentiator and anti-Covid agent
  • Atremorine capsules
  • Institutional rebranding
  • New international scientific publications
Prevention Covid-19 Euroespes


Nº2, July 2020

  • Anti-Covid-19 campaign
  • DefenVid exports to Brazil
  • Dopaminergic effect of Atremorine in Parkinson's disease
  • The Pharmacogenetic Smart Card
  • Epigenetic biomarkers
Sars Medical Bulletin Covid 19 Euroespes


Nº3, August 2020

  • SARS-Covid-19: Challenges and Recommendations
  • EuroEspes Health Kit: A System for Home Analyses
  • BrainRex: new bioproduct for Alzheimer's disease
  • New cocoa-derived bioproducts

Nº4, September 2020

  • Alzheimer's prevention plan
  • Epinutraceuticals
  • Epigenetic effect of Atremorine in Parkinson's disease
  • Genomics of language disorders
  • Covid News-19

Nº5, October 2020

  • COVID-19 News
  • Epidemiology and Mortality Rates
  • Prophylactic Recommendations
  • Herd immunity
  • COVID-19 Genetics and Pharmacogenetics

Nº6, November 2020

  • Atremorine patent
  • Alzheimer's Prevention Plan
  • Treatments for Headache
  • Effects of Cannabis use
  • COVID-19 News

Nº7, December 2020

  • 2020: The Year of Global Covidisation
  • Prevalent Disease Prevention Plans
  • COVID-19 News
  • Launch of Atremorine capsules
  • Launch DefenVid-90

Nº8, January 2021

  • Editorial January: Don't abandon the chronically ill
  • Prevention Plans against neurodegenerative diseases
  • Dopamine Transporter Genetic Variants Influence Drug Response in Parkinson's Disease
  • COVID-19 News
  • Expansion of EuroEspes in Brazil


Nº9, February 2021

  • Editorial February o Stop violating people's freedom
  • New treatments for Alzheimer's disease, Parkinson's disease and stroke
  • Powerful epigenetic effect of Atremorine
  • Ebiotec announces the upcoming launch of NeoBrainine
  • COVID and the Brain
  • Genetics and treatment of Amyotrophic Lateral Sclerosis (ALS)
  • Genetics of Autism
  • Complete map of the Human Genome
  • DermoGenomics


Nº10, March 2021

  • Editorial March: A Year of Erratic Confusion
  • New Epigenetic Biomarkers for Alzheimer's Disease
  • EuroEspes: World leader in the development of epinutraceutical bioproducts
  • COVID-19 News
  • EuroEspes is implemented in Brazil
  • Managing Director of EuroEspes and Technical Director of Ebiotec
  • Dr Cacabelos, new Editor-in-Chief of the Journal of Genomic Medicine and Pharmacogenomics


Nº11, April 2021

  • Editorial Abril: Morality and Ethics in Crisis
  • Ebiotec launches NeoBrainine, a neuroprotective agent for dementia and strokes
  • Depression and Anxiety: more frequent in women than in men.
  • Specialised services in Health Biotechnology
  • Industrial freeze-drying for the food industry
  • COVID-19 News
  • Dr. Ramón Cacabelos, new Editor-in-Chief of Central Nervous System
  • Agents in Medicinal Chemistry


Nº12, May 2021

  • Editorial May: Conditional Normality
  • Prevalent Diseases Prevention Campaign
  • New Genomic Biomarker for Alzheimer's disease
  • Nutraceutical Biotechnology
  • COVID-19 News
  • Promotional Section

Nº13, June 2021

  • Editorial June: Integrity

  • Powerful effect of Atremorine in the personalised treatment of Parkinson's disease

  • FDA approves Aducanumab (Aduhelm®) for the treatment of Alzheimer's disease

  • Complete sequencing of the Human Genome

  • COVID-19 News

  • EuroEspes creates a prestigious Ethics Committee

  • Editorial News

  • Promotional Section

Nº14, July 2021

  • Editorial July: Educating for Health

  • Adverse drug reactions

  • Breakthroughs in molecular imaging of the brain

  • Epigenetic biomarkers for early diagnosis and therapeutic monitoring and therapeutic monitoring

  • Microbiome and the Brain-Gut Axis

  • COVID-19 News

  • Dr. Ramón Cacabelos, Fleming Award for Healthcare Excellence 2021

Nº15, August 2021

  • Editorial August: Things worth remembering

  • Therapeutic Paradigm Shift in the Treatment of Alzheimer's disease

  • Oncogenic stem cells

  • Alarming increase in Diabetes

  • Criteria for diagnosing and treating migraines

  • OCD genetic sequencing

  • Oxytocin and Maternal Behaviour

  • COVID-19 News

Nº16, September 2021

  • Editorial September: Gratitude and Fidelity
  • 30 Years of Community and Health Service
  • Neovital adds Ebiotec products to its commercial portfolio
  • Tobacco use during pregnancy
  • Initiatives to sequence the genome of newborns
  • Genuine epigenetic differences in identical twins
  • Obsessive-Compulsive Disorder (OCD) brain endophenotypes
  • COVID-19 News

Nº17, October 2021

  • EditorialOctober: MentalHealth Turbidities
  • EuroEspesannounces new epinutraceutical bioproduct for the prevention ofAlzheimer'sdisease
  • EuroEspesscientistsdiscover thatAlzheimer'sdisease patientsaccumulatealarge number ofdefectivegenesin their genome.
  • XenoestrogenicSyndrome: The high price of contraceptives and hormonereplacementtherapy
  • COVID-19News

Nº18, November 2021

  • Editorial November: Cholinergic theory and acetylcholinesterase inhibiting agents in the treatment of Alzheimer's disease: An interesting history

  • Alzheimer's disease almost never comes alone

  • Psilocybin for treatment of depression

  • Serotonin's role in brain disorders and social memory

  • The need for bioinformatics to manage and interpret genomic information

  • The genetic secrets of ancient fish

  • Influenza mRNA vaccines

  • COVID-19 News

Nº25, June 2022

Nº26, July 2022

Nº27, August 2022

Nº28, September 2022

Nº29, October 2022

Nº30, November 2022

Nº31, December 2022

Nº32, January 2023

Nº33, February 2023

Nº34, March 2023


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