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Logotipo de Euroespes Health que presenta un cerebro estilizado formado por líneas rojas y azules entrelazadas a la izquierda, que simboliza las "pruebas avanzadas para detectar el Parkinson". Las palabras "euroespes health" están escritas en minúsculas a la derecha sobre un fondo oscuro.
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VII Annual Euroespes Conference

New horizons in the prevention and personalized treatment of neurodegenerative diseases.

Personalized Medicine

Scientists from the International Center for Neuroscience and Genomic Medicine present new models of preventive intervention and personalized treatment for Alzheimer's and Parkinson's disease at the 4th Meeting of the World Association for Genomic Medicine.

Alzheimer's disease and Parkinson's disease are the two most important neurodegenerative disorders and the main causes of disability in developed countries. Alzheimer's disease affects 50 million people worldwide, with an average patient/year cost of 20,000 euros; and Parkinson's disease has a prevalence of more than 1,700 cases per 100,000 inhabitants in the population over 65 years of age, affecting more men than women. Both diseases have been a priority topic of scientific debate at the IV Meeting of the World Association of Genomic Medicine (WAGEM), chaired by Dr. Ramón Cacabelos, Professor of Genomic Medicine and President of the EuroEspes International Center for Neurosciences and Genomic Medicine, in A Coruña.

The main conclusions of this scientific event were:

  • Neurodegenerative diseases result from the confluence of genetic, epigenetic and environmental factors.
  • The neurodegenerative disorders associated with Parkinson's and Alzheimer's are destroying our neurons several decades before they show symptoms.
  • Predictive biomarkers are needed to identify the population at risk before the disease manifests.
  • Treatments should be aimed at protecting neurons against a premature death process rather than treating symptoms.
  • All treatments should be personalized based on the pharmacogenetic profile of each patient.
Un panel de seis personas se sienta en una mesa larga durante una conferencia. Detrás de ellas hay una pancarta que anuncia la Conferencia Anual sobre Medicina Personalizada para Trastornos Neurodegenerativos. En la sala se ven una pantalla y dos arreglos florales.

In this context, scientists from the EuroEspes Medical Center presented new advances in the EB-101 vaccine against Alzheimer's disease.Dr. Ivan Carrera, head of the Health Biotechnology department presented the first studies with Atremorine, a new product for the prevention and treatment of Parkinson's disease, which protects dopaminergic neurons damaged in Parkinson's; and Dr. Cacabelos showed the first clinical results with Atremorine, recently published in the Journal of Genomic Medicine and PharmacoGenomics and in the Journal of Exploratory Research in Pharmacology.

Dr. Juan Carlos Carril, Secretary General of the Spanish Society of Genomic Medicine, and Dr. Oscar Teijido, Secretary General of WAGEM emphasized the role of genomics and epigenetics in the risk of stroke and degenerative diseases, respectively. Dr. Andrius Baskys, Vice-President of WAGEM in California, showed results of a study in the USA in which it was demonstrated that American psychiatrists improved their therapeutic precision in the treatment of psychiatric patients when they personalized the prescription of psychotropic drugs through the use of pharmacogenetic procedures. Another problem of growing interest is brain neurodegeneration following microtraumatic brain injuries, a subject addressed by Dr. Steve Sclan, from Florida, for which there is no defined treatment.

Dr. Cacabelos echoed the concern of the medical community and families about the lack of specific treatments for Alzheimer's disease, based on the fact that the international pharmaceutical industry has been unable to obtain a single effective drug, after more than 400 failed trials with new molecules in the last 15 years. He also emphasized the convenience of personalizing Parkinson's treatment to reduce the toxicity and side effects generated by antiparkinsonian drugs in patients condemned to consume them for life; but, above all, he made it clear that the fight against neurodegenerative diseases will only be effective by intercepting the process of neuronal death with preventive strategies in the population at risk years before the disease manifests itself clinically.

Una persona da una presentación sobre medicina personalizada. Se muestra una diapositiva sobre "Cambios endocrinos y síntomas menopáusicos". Sobre una mesa junto a ella hay una flor de pascua decorativa y un libro.
Pleiotropic properties of Mineraxin in perimenopausal state.
Dr. Lola Corzo.
Una persona está de pie en un podio con un micrófono y presenta diapositivas en una pantalla sobre un estudio científico relacionado con la dopamina. La pancarta a su lado dice "EuroEspes Medicina Personalizada" con un logotipo debajo.
EuroEspes Biotechnology Nutraceutical Catalogue: Biotechnological Strategies for Prevalent Diseases.
Dr. Lucía Fernández-Novoa
Un hombre da una presentación sobre traumatismo craneoencefálico en una conferencia. En la pantalla se muestran diapositivas que explican las diferentes causas del traumatismo craneoencefálico. El podio está decorado con un jarrón de flores rojas y una pancarta.
Mild brain trauma and post-concussion syndrome: clinical description, neuropathological criteria and potential pharmacogenomic intervention strategy.
Dr. Steve Sclan.
Un hombre con traje habla en un podio durante la Conferencia Anual de EuroEspes. A su lado hay una pancarta y una flor de pascua. El evento se centra en la medicina personalizada y la farmacogenómica.
The application of pharmacogenomics in clinical practice promotes the development of simple bioinformatics tools.
Dr. Andrius Baskys.
Un hombre con traje hace una presentación en un podio durante la VII Conferencia Anual de EuroEspes. En una pantalla se muestra una diapositiva titulada "Estudios preclínicos de línea tumoral humana (cribado in vitro)". Sobre la mesa hay una maceta con una flor de pascua.
Antitumor effects of Antigan / Advances in Alzheimer's vaccine: EB-101.
Dr. Iván Carrera.
Un hombre de traje da una presentación en un podio, señalando una diapositiva titulada "Interacción con otros medicamentos" en una pantalla. En la mesa a su lado hay una flor de pascua en una maceta. En la pared de la sala hay un cartel que dice "Medicina personalizada".
Cardiovascular disease and new anticoagulant drugs.
Dr. Juan C. Yánez.
Una persona está de pie en un podio, dando una presentación con una presentación de diapositivas de fondo. El escenario parece ser el de una conferencia, con carteles visibles sobre medicina genómica y trastornos neurodegenerativos. Una planta de flor de pascua decora el podio.
Genomics of cerebrovascular diseases / EuroPharmacGenics (EPG) database.
Dr. Juan C. Carril
Un hombre habla en un podio durante una conferencia médica. Hay una diapositiva de presentación con diagramas de ratones relacionados con los efectos epigenéticos. El fondo muestra carteles de conferencias sobre trastornos neurodegenerativos y medicina personalizada.
Epigenetics of neurodegenerative diseases.
Dr. Óscar Teijido
Un hombre con barba y gafas habla en un podio con micrófono. Lleva traje gris y corbata negra. Detrás de él hay una pancarta con un texto relacionado con la medicina personalizada y la genómica.
Influence of genomic factors in ophthalmologic disorders.
Dr. Carlos Sevillano
Una mujer se encuentra en un podio para realizar una presentación en la conferencia anual de EuroEspes. Una pantalla grande muestra una imagen médica. Se ven pancartas con detalles de la conferencia y un arreglo floral.
Rhinosinusitis: age, sex, imaging and genomics.
Lucia Lopez
Un orador está dando una conferencia en una sala con asistentes sentados. Una pantalla muestra una diapositiva con diagramas y texto. El evento se centra en la medicina personalizada, como lo indica la señalización en el fondo.
New therapeutic strategies and pharmacogenomics of Parkinson's disease.
Dr. Ramón Cacabelos
Un hombre de traje habla en un podio, con papeles en la mano. En el fondo se puede leer "EuroEspes Medicina Personalizada", lo que sugiere una conferencia o presentación sobre medicina personalizada.
Brain mapping and optical topography of dementia: genomic correlates.
Iván Tellado
Gráfico con tres cuadrados superpuestos. Uno muestra "Prevención" con una imagen de microscopio, otro "Diagnóstico precoz predictivo" con imágenes de ADN y el tercero "Tratamiento personalizado" con una mano que sostiene pastillas. Patrones geométricos en el fondo.

EuroEspes - Personalized Medicine

The EuroEspes International Center for Neurosciences and Genomic Medicine is a world pioneer in the implementation of Personalized Medicine based on knowledge of the Human Genome. In 2016 it celebrates 25 years since its foundation. It has a team of researchers in genomic medicine, pharmacogenetics and diseases of the Central Nervous System with extensive international experience in Japan, the United States, the United Kingdom and India, who have participated in 2,000 scientific publications and in the development of various patents.

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