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Incidencia, prevalencia y carga mundial de esquizofrenia

La esquizofrenia contribuye sustancialmente a la carga de trastornos mentales. Se han publicado estimaciones epidemiológicas y de la…

Los matemáticos descubren una nueva clase de forma

Los matemáticos han descrito una nueva clase de forma: las células blandas. Estas formas tienen esquinas que se…

Componente predictivo del cerebro humano

Nuestro cerebro reconoce constantemente patrones en la vida cotidiana, incluso sin que seamos conscientes de ello. Los investigadores…

A vueltas con la patogenia de la enfermedad de Parkinson

Huw R Morris, Maria Grazia Spillantini, Carolyn M Sue y Caroline H Williams-Gray revisan la patogenia de la…

Un retrato de los cambios cerebrales durante el embarazo

Un estudio muestra 26 resonancias magnéticas del cerebro de una mujer durante su primer embarazo para registrar con…

Inteligencia Artificial Científica

¿Se podría automatizar por completo la ciencia? Un equipo de investigadores de aprendizaje automático ha intentado hacerlo posible….

Tratamiento del Cáncer de Pulmón

Hasta el año 2000, el cáncer de pulmón era una enfermedad muy letal. Las opciones de tratamiento eran…

El líquido espinal podría causar migraña

¿Qué causa las migrañas? El estudio del “apagón cerebral” ofrece pistas. Los dolores de cabeza que causan ceguera…

¿Realmente sabemos cómo actúan los antidepresivos?

En los laboratorios del Imperial College de Londres, Reino Unido, los investigadores están estudiando cómo pequeños grupos de…

Safety and efficacy of Atogepant in the treatment of migraine headaches

Atogepant, an oral peptide receptor antagonist related to the calcitonin gene, has been approved for...

Pharmacogenetics vs. conventional treatment in schizophrenia

Zhewei Kang, Ying Qin, Yutao Sun and colleagues studied the impact of multigenetic pharmacogenomics-guided treatment (MPGT)...

Myasthenia gravis

Myasthenia gravis is an autoimmune neuromuscular disorder that causes muscle weakness. This occurs because the immune system...

Losmapimod in facioscapulohumeral muscular dystrophy

Facioscapulohumeral muscular dystrophy is an inherited progressive myopathy caused by aberrant expression of the transcription factor...

Profile of Eating Disorders

It has been more than 70 years since the first eating disorder, anorexia nervosa, was included in...

Safety and efficacy of Glenzocimab in patients with acute ischemic stroke.

Antagonists of glycoprotein VI-triggered platelet activation used in combination with recanalization therapies are...

How to rejuvenate an aging immune system?

Antibodies that target blood stem cells can rejuvenate immune responses in mice. The...

Association of spinal cord atrophy and brain lesions in Multiple Sclerosis.

Progression independent of recurrent activity (PIRA) is a crucial determinant of the overall accumulation of disability....

Contribution of vaccination to improved survival and health.

WHO, at the request of its member states, launched the Expanded Program on Immunization (EPI) in 1974 to...

WHO guideline for measuring hemoglobin in the definition of anemia

Anemia is conventionally determined when the hemoglobin concentration falls below a defined threshold for...

Blood pressure control in acute ischemic stroke

Intravenous thrombolysis is contraindicated in patients with ischemic stroke with blood pressure greater than 185/110 mm Hg.....

Selective eradication of hematologic cancer with preserved hematopoiesis.

Hematopoietic stem cell transplantation (HSCT) (HSCT) is the only curative treatment for a wide range of...

Bariatric surgery in women with polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility. Obesity exacerbates the...

Epilepsy in Alzheimer's disease

A growing body of evidence has shown a link between Alzheimer's disease (AD) and epilepsy....

MAPT H2 haplotype and risk of Pick's disease.

Pick's disease is a rare and predominantly sporadic form of frontotemporal dementia that is classified as...

Genomics reveals mutation promoting agents

Genetic sequencing of human kidney cancers around the world has revealed associations between geographic locations...

Epigenetic reprogramming of laboratory-cultured sperm and eggs

According to Heidi Ledford, the day when human sperm and eggs can be cultured in the laboratory...

Molecular mechanism of choline and ethanolamine transport in humans.

The feline leukemia virus subgroup C receptor-related proteins 1 and 2...

Genomic Imprinting

Some genes carry a "fingerprint" in the maternal or paternal copy, which determines whether that copy is expressed...

Causes of Death

Regular and detailed population health reporting by underlying cause of death....

Global Morbidity and Mortality

Future trends in disease burden and health factors are of great interest to...

COVID extended in England

The term prolonged COVID, also known as post-COVID-19 condition, was coined in the spring of 2020 by people...

World Fertility

Accurate assessments of current and future fertility, including general trends and changes in fertility rates, are...

Stroke prevention in patients with atrial fibrillation

Atrial fibrillation is one of the most common cardiac arrhythmias and is a major cause of stroke....

Selective anti-tumor activity by RAS-GTP inhibition with RMC-7977 in pancreatic cancer.

Broad-spectrum SAR inhibition has the potential to benefit approximately one-quarter of the world's...

Posterior Cortical Atrophy

Posterior cortical atrophy is an uncommon syndrome characterized by an early, prominent and progressive deterioration in...

Percutaneous coronary intervention guided by intravascular ultrasound versus angiography in acute coronary syndromes.

Intravascular ultrasound-guided percutaneous coronary intervention has been shown to produce superior clinical outcomes compared to...

Epidemiology of motor neuron disease

Understanding how the prevalence, incidence and mortality of motor neuron diseases change with...

Conflicting information on the use of valproic acid in pregnancy.

Regarding an Editorial in the Lancet Neurology on the use of valproic acid (Reducing the uses of...

Ketamine versus ECT for nonpsychotic treatment-resistant major depression

Electroconvulsive therapy (ECT) and subanesthetic intravenous ketamine are currently used for major depression resistant to...

mRNA therapy for propionic acidemia

Propionic acidemia is an inherited metabolic condition caused by the lack of a liver enzyme, which causes...

Glycemic control in Diabetes-II

Prospective 20-year diabetes study in the United Kingdom showed significant clinical benefits for people with...

50 years of history of Immunization Programs

On May 23, 1974, at the 27th World Health Assembly in Geneva, Switzerland, the...

Discovery of small molecules with potent activity to inhibit the formation of lipoproteins.

Lipoprotein (a) (Lp (a)), an independent causal cardiovascular risk factor, is a lipoprotein particle that...

Parkinsonian psychosis

Parkinson's disease (PD) psychosis (PDP) is a spectrum of delusions, hallucinations and delusions that...

New Genetic Defect Associated with Parkinson's Disease

Parkinson's disease is defined by the presence of progressive motor dysfunction, but many patients also experience...

Leucine-rich glioma inactivated protein 1-inactivated encephalitis

Leucine-rich glioma inactivated protein 1 encephalitis (anti-LGI1 encephalitis) is a rare neurological disease that...

Progressive Multifocal Leukoencephalopathy Biomarkers

Progressive multifocal leukoencephalopathy is a rare but devastating demyelinating disease caused by the JC virus (JC virus), a...

Implications of the genetics of schizophrenia.

There have been substantial advances in understanding the genetics of schizophrenia in the last 15 years....

Tranexamic Acid in intracerebral hemorrhage

Tranexamic acid, an antifibrinolytic agent, could attenuate hematoma growth after intracerebral hemorrhage. The...

Prevalent Population Health Risk Factors

Understanding the health consequences associated with exposure to risk factors is necessary to inform...

Concurrent inhibition of oncogenic RAS-GTP for cancer therapy.

The RAS oncogenes (collectively NRAS, HRAS and especially KRAS) are among the most frequently mutated genes in...

Giving Meaning to Life (II)

The infallible formula for not wasting is not spending. Many people despise life by wasting the precious time they have...

Should cerebral cavernous malformations be operated on?

Patients who have an identified cerebral cavernous malformation due to a seizure or focal deficit have...

Mortality and Life Expectancy

Estimates of demographic metrics are crucial for assessing levels and trends in health outcomes....

Laquinimod in Huntington's disease

Laquinimod modulates CNS inflammatory pathways believed to be involved in the pathogenesis of...

Brain death

The declaration of brain death (BD), or death by neurological criteria (DNC), is medically and legally accepted in...

Ticagrelor versus ticagrelor plus aspirin in patients with acute coronary syndromes.

After percutaneous coronary intervention with stent placement to treat acute coronary syndromes, clinical guidelines...

A global treaty against the pandemic

Millions of people died from COVID-19 because during the outbreak the fundamental principle of fairness among...

Fentanyl addiction

Neuroscientists have discovered that two distinct neural pathways are responsible for the addictive properties of the opioid fentanyl:...

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